Introductory scenario The local hospital asks the manager of a small laboratory

Question

Introductory scenario The local hospital asks the manager of a small laboratory to start testing for Disease Marker X (DMX), a low- molecular-weight analyte. DMX is used to detect Disease X, which is very serious and causes high rates of fatality at low concentrations. Although testing for DMX has historically been a send-out test, the laboratory manager has been asked to bring the analysis in-house because many patients have developed Disease X in the local community Note: Disease Marker X and Disease X are hypothetical examples used for illustrative purposes in this case study. Continue to questions Chapter 11 Labeled Immunoa

Explanation / Answer

1.The correct answer is:B. Such testing can measure antigen or antibodies that are present in low concentrations.

Reason: Since DMX is fatal at low concentrations,immunoassay will help detect its presence even at low concentrations.

2.The correct answer is:A. The EIA test

Reason: EIA is less expensive as it does not require use of radio isotopes and radiation counter used in radioimmunoassay that are costly.

3.The correct answer is:B.Homozygous EIA.

Reason:Homozygous EIA helps detect small amounts of antigen at a faster and easier way as it does not involve separation of antigen antibody complex formed.

4.The correct answer is: B.The patient has a low concentration of DMX.

Reason:When sample antigen is less and labelled antigen is more , then more of the labelled antigen will remain and that will give a strong color or we can say that color production is inversely proportional to concentration of test antigen present in sample.

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