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etne to your article or references within: 7) What are teratogenic effe ratogeni

ID: 926646 • Letter: E

Question

etne to your article or references within: 7) What are teratogenic effe ratogenic effects? Which isomer is thought to exhibit these properties? (5 pts) ere imb teratsenic efeets ic effeets inelude bieth defects such as reduchion. The Cs)-tsomer is associouted witt 8) Why is it impossible to have only one enantiomer of thalidomide under biological conditions? (3 pts) enaome can rocemce fue to e aeidic ydvogen ot the Chora cuuttre 9) Why might 3-fluorothalidomide be a better mimic of thalidomide than 3-methyl thalidomide? (3 pts)

Explanation / Answer

The answers to first two questions are correct.

No:3 3-fluorothalidomide is a better mimic of thalidomide than 3-methyl-thalidomide as you must be knowing that it is easier to control reactions (specially nucleophilic reactions) concerning halogens than those containing aliphatic chains as aliphatic bond formation is considered one of the difficult reactions. Thus, it is convinient to use a halogen with options of further substitutions or any other kind of reactions those can be operated with less difficulty unlike in case of 3-methylthalidomide.