steroid nandrolone, which is found naturally in horses, is administered to racin
ID: 915161 • Letter: S
Question
steroid nandrolone, which is found naturally in horses, is administered to racing horses to aid in covery. Because it is an anabolic steroid, nandrolone levels in excess of normal background levels squality a horse from racing. For example, to race in the Kentucky Derby, a gelding (a castrated male orse) may have no more than 1 ng/mL in the urine, whereas an unaltered male horse may have no more an 45 ng/mL of the metabolite estrange-3, 17 -diol in the urine. Knowing that nandrolone in an anabolic steroid, which of the following hormones would you except it to closely resemble? During metabolism, carbon 3 and carbon 4 of nandrolone are reduced, forming the metabolite estrane-3, 17 -d. Modify nandrolone, below, to give estrange-3, 17-diol.Explanation / Answer
Knowing that the nandrolone is anabolic steroid, testosterone would resemble it closely.
Because the structure of both nandrolone and testosterone are almost similar except the methyl group present at 19 position in testosterone.
Moreover nandrolone has similar effects to body but with lesser extent compared to testosterone.
Testosterone has anabolic as well as androgenic activity while nandrolone has only anabolic activity.
The metabolite of nandrolone I.e. 19-norandrosterone is used as a detection parameter for the doping test in athletes.
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