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Which of the following descriptions is not correct? (A) The leucine zipper motif

ID: 90953 • Letter: W

Question

Which of the following descriptions is not correct?

(A) The leucine zipper motif is important for protein-DNA interaction.

(B) Ribozymes are RNA molecules with catalytic activity.

(C) The poly(A) tail can stimulate recruitment of the 40s ribosomal subunit to mRNA; therefore, it is important in initiation of protein synthesis.

(D) Diphtheria toxin can inhibit mammalian RNA synthesis by reduction the elongation factor-2 activity.

(E) The suppressor tRNA molecules are capable of suppressing missense mutations.

Explanation / Answer

Answer:

(D) Diphtheria toxin can inhibit mammalian RNA synthesis by reduction the elongation factor-2 activity

Explanation:

Corynebacterium diphtheriae, infected with a specific lysogenic phage, produces an exotoxin that catalyzes the ADP-ribosylation or eEF-2 in mammalian cells. The toxin inhibit protein synthesis.

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