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Print Calculator Periodic Table uestion 8 of 9 Map sapling leaming Enzymes use s

ID: 906845 • Letter: P

Question

Print Calculator Periodic Table uestion 8 of 9 Map sapling leaming Enzymes use several types of catal mechanisms. Differentiate between acid-base catalysis, Covalent catalysis, and metal ion catalysis (If you answer any part of this question incorrectly, a single red X will appear indicating that one or more of the phrases are sorted incorrectly.) Acid-base catalysis Covalent catalysis Metal ion catalysis All catalysts may participate a Zn cofactor may properly orient may take part in in oxidation-reduction reactions interactions the substrate in the active site by changes in the oxidation state through ionic interactions involving Fe a proton is a covalent bond lowers the energy or catalyst retains stabilizes the transition its original form transferred between forms between state or intermediate after reaction occurs enzyme and substrate enzyme and substrate two-part catalytic process uses a nucleophilic may use amino acids such as (for example, the functional group aspartate or lysine for chymotrypsin mechanism protonation or proton abstraction

Explanation / Answer

Acid-base catalysis : A proton is transferred between enzyme and substrate , may use amino acids such as aspartate or lysine or protonation or proton abstarction , Two part catalytic process ( example chymotrypsin)

Covalent catalysis - A covalent bond forms between enzyme and substrate , uses a nucleophilic functional group

Metal-ion catalysis - A Zn2+ cofactor may properly orient the substrate in the active site through ionic interactions , may take part in interactions involving Fe2+ , catalysyts may participate in oxidation-reduction reactions by change in oxidation state

All - Lowers the energy or stabilizes the transition state or intermediate , catalysts retain its original form after reaction occurs

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