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Homework ti4 Due 6/12 (MONDAY at beginning of recitation) NAME Complementation t

ID: 90540 • Letter: H

Question

Homework ti4 Due 6/12 (MONDAY at beginning of recitation) NAME Complementation tests Seven different recessive point mutations (1-7) that cause uncoordinated movement in C elegans were isolated. The table F1 resulted numbered 1-7) homozygous for each mutation below shows the phenotypes that when strains were crossed; "u" indicates uncoordinated and "t" indicates normal. l) Based on these results, how many different GENES are affected by these seven mutations? 2) How many of the genes (from the previous answer) are represented by ONLY 1 of the seven mutant alleles? Which mutation(s) affect(s) this/these gene(s)? Mutation(s) that affect this/these gene(s) (list by number of genes with one mutation 3) Extra credit: In a subsequent experiment, the Fl's resulting from the cross between strains 3 and 7 (which, as the table indicates, are phenotypically normal were mated to the "4 x 6" Fi's (i.e., the progeny of the cross between strains 4 and 6, which are also norma Assuming a mutations are strictly recessive, what fraction of the resulting progeny should be uncoordinated?

Explanation / Answer

Answer:

1. Based on the results, it is clear that when each strain having mutation is self-crossed, they show uncoordinated movements. So, there are ten (10) genes that are affected by the seven mutations.

2. a. There are four (4) genes that are represented by one of the seven mutant alleles.

b. The mutations that affect these genes are (4), (5), (6) and (7) mutation.