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From the preparation of an antihepatitus C antiviral agent (Org Lett 2014, 16, 4

ID: 894092 • Letter: F

Question

From the preparation of an antihepatitus C antiviral agent (Org Lett 2014, 16, 4878). The following reaction is proposed to occur in one experimental step (A to B), proceeding through the intermediate (I). Look carefully at the individual transformations and classify them (A to I) and (I to B), anticipate the number of steps in each mechanism, as well as what those steps would be, and then draw out the detailed, step-wise, curved arrow mechanisms. Use H-B as your generic Bronsted acid, and B: as its conjugate base.

Explanation / Answer

From the preparation of an antihepatitus C antiviral agent (Org Lett 2014, 16, 4

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