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Periodic Table Question 27 of 28 sapling The isoelectric point (pl) of a peptide

ID: 886460 • Letter: P

Question

Periodic Table Question 27 of 28 sapling The isoelectric point (pl) of a peptide is the pH at which the peptide does not migrate in an ele number of positive charges as negative charges on the peptide population. The pl can be estimated fairly accurately (within 0.1 or 0.2 pH units) from the pK values of all the proton dissociable groups in the peptide. Using pK values from the table at the right, estimate the pl value of the ld. Since the peptide is zwitterionic, there are the same Amino Side Acid Chain pk 12.5 ng hexapeptide 8.2 4.3 6.0 10.5 10.5 'peptide-8.0 Gly-His-Glu-Lys-Phe-Cys Glu Lys Tyr NH3 3.4 from the amino and carboxy values of a single amino acid

Explanation / Answer

Isoelectric point = 7.44

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