This equation will estimate a greater distance than the formula given in the boo

Question

This equation will estimate a greater distance than the formula given in the book: RF= (2* [Tetratypes] + 4* [Non-parental ditypes])/4* [Total Tetrads] Why does the deviation between the estimates from the two formulas decrease as the two loci become more tightly linked? What does 4 times the number of total tetrads equal to? If you get this, then what does 2 time the tetratypes equal to? 4 times the non-parental ditypes? Why are we not multiplying the parental ditypes by anything? So what does the formula in b estimate? What does our formula estimate that this formula does not? Your answer in iii gives you the reason for the deviation in the two estimates. Why does this deviation decrease in tightly linked loci?

Explanation / Answer

4 times the number of total tetrads is equal to 4* [Total tetrads] = 16 tetrads

4* [Total tetrads] = (2* [Tetratypes] 4* [Non-parental ditypes)/RF

                          (2* [Tetratypes] = 4* [Non-parental ditypes)/ 4* [Total tetrads]X RF

4* [Non-parental ditypes]=(2* [Tetratypes] / 4* [Total tetrads]X RF

Because parental ditypes are similar

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