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Question 5 options: Fill in the blanks below to appropriately complete the follo

ID: 885287 • Letter: Q

Question

Question 5 options:

Fill in the blanks below to appropriately complete the following text:

A protein's tertiary structure is determined by a number of factors and forces including:

1) hydrogen bonding

2) ______________ forces which are defined as the weak forces of attraction between hydrophobic moieties such as between hydrophobic 'R' groups on amino acids in close proximity to one another

3) Disulfide (i.e. -S=S-) linkages that develop between the sulfhydryl (aka _____________) functional groups on cysteine amino acids in close proximity to one another

4) ___________ defined as those bonds that form between oppositely charged side groups on amino acids in close proximity to one another

and

5) _____________ sequestration that causes non water soluble segments of the protein to move toward the interior of the molecule (i.e. to move away from the surrounding aqueous environment) while more water soluble segments remain at the molecule's perimeter.

Explanation / Answer

1- Hydrogen bonding form between different side-chain groups.

2- Hydrophobic forces forces which are defined as the weak forces of attraction between hydrophobic moieties such as between hydrophobic 'R' groups on amino acids in close proximity to one another.

3-  Disulfide (i.e. -S=S-) linkages that develop between the sulfhydryl (aka Covalent bond) functional groups on cysteine amino acids in close proximity to one another

4) Electrostatic forces defined as those bonds that form between oppositely charged side groups on amino acids in close proximity to one another

5) Polar interial sequestration that causes non water soluble segments of the protein to move toward the interior of the molecule (i.e. to move away from the surrounding aqueous environment) while more water soluble segments remain at the molecule's perimeter.

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