Several prostaglandin derivatives were synthesized in the lab and tested for the

Question

Several prostaglandin derivatives were synthesized in the lab and tested for their ability to sensitize a prostaglandin-specific G-protein coupled receptor and modulate cholesterol metabolism. According to the information below, which of the prostaglandin derivatives (PD) would form the most stable complex with the receptor? A. PD1, K_D = 1 nM B. PD2, K_D = 1 mu M C. PD1, KM = 1 nM D. PD2, K_D = 1 mu M In the CAMP-dependent activation of pyruvate kinase, which of the following amino acids is phosphorylated? A. His B. Thr C. Tyr D. Ser E. Lys

Explanation / Answer

answer:

73)B.PD2,KD=1um most stable complex with the receptor

74)E.LYS amino acid that is phosphorylated

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