Question 25 Could something liver like inflammation be an acute outcome for expo

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Question 25

Could something liver like inflammation be an acute outcome for exposure to some chemical and a chronic outcome the same chemical? What is the level of cancer risk that is usually considered "acceptable" by regulators? and where does that number come from? Define LD50. And, is LD50 used in a chronic or acute context? For rats, the LD50 for THC, the active chemical in marijuana, is given as 1.27 g/kg. From the point of view of DEATH as the endpoint, is the highly toxic? Who was Percival Pott and what does he have to do with the history of the study of cancer? Section 3. Pesticides, Chlorinated Dioxins, Chlorinated Furans, PCBs, PBBs, and PBDEs Looking at a chemical structure, what two primary chemical characteristics are found in legacy insecticides?

Explanation / Answer

27. Define LD50

And is LD50 used in a chronic or acute context.

LD50 is know as Lethal Dose 50%. So basically it is the amount of substance required to kill 50% of the group of test animals. And mostly this LD50 is used against mice or rats.

And it is used in acute context because LD50 is used for measuring the short - term potential for poisoning of tested animals.

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