8. In dogs there are three autosomal, independently assorting allelic pairs with

Question

8. In dogs there are three autosomal, independently assorting allelic pairs with the following genotype-phenotype relationships:

B,b Codominance; BB = black, Bb = spotted (black & tan), bb = tan
G,g G (grey eyes) completely dominant to g (yellow eyes)
L,l Incomplete dominance; LL = normal liver, Ll = diseased liver, ll = no liver (lethal)

In addition, the L,l allelic pair is subject to abnormal transmission ratios in males only, such that heterozygous males transmit 70% l-bearing sperm and 30% L-bearing sperm.

A. In the cross of a female BbGgLL to a male BbGGLl, what proportion of the black, grey-eyed, normal-livered progeny will be homozygous for all three genes?

B. Of the living progeny of the following cross, what is the probability of obtaining a spotted, grey-eyed, normal-livered puppy?

BbGgLl female x bbGgLl male

Explanation / Answer

Its given that BB = black, Bb = spotted (black & tan), bb = tan GG, Gg - Grey eyes, gg - yellow eyes LL = normal liver, Ll = diseased liver, ll = no liver A. BbGgLL * BbGGLl BGL BgL bGL bgL BGL BBGGLL BBGgLL BbGGLL BbGgLL BGl BBGGLl BBGgLl BbGGLl BbGgLl bGL BbGGLL BbGgLL bbGGLL bbGgLL bGl BbGGLl BbGgLl bbGGLl bbGgLl BGL BgL bGL bgL BGL BBGGLL BBGgLL BbGGLL BbGgLL BGl BBGGLl BBGgLl BbGGLl BbGgLl bGL BbGGLL BbGgLL bbGGLL bbGgLL bGl BbGGLl BbGgLl bbGGLl bbGgLl
Only one progeny will be homozygous for all three genes. B. BbGgLl x bbGgLl BGL BGl BgL Bgl bGL bgL bGl bgl bgL BbGgLL BbGgLl BbggLL BbggLl bbGgLL bbggLL bbGgLl bbggLl bgl BbGgLl BbGgll BbggLl Bbggll bbGgLl bbggLl bbGgll bbggll bGl BbGGLl BbGGll BbGgLl BbGgll bbGGLl bbGgLl bbGGll bbGgll bGL BbGGLL BbGGLl BbGgLL BbGgLL bbGGLL bbGgLL bbGGLl bbGgLl
SIX of all th eprogeny will be spotted, grey eyed and normal livered puppies. -BbGGLL. BbGgLL BGL BgL bGL bgL BGL BBGGLL BBGgLL BbGGLL BbGgLL BGl BBGGLl BBGgLl BbGGLl BbGgLl bGL BbGGLL BbGgLL bbGGLL bbGgLL bGl BbGGLl BbGgLl bbGGLl bbGgLl

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