J.W., at age 5 months, has a moist, erythematous rash on the cheeks, chest, and

Question

J.W., at age 5 months, has a moist, erythematous rash on the cheeks, chest, and extensor surfaces of the arms, caused by atopic dermatitis. She had a secondary bacterial infection on one cheek.

1. State the factors in the family history that may support a genetic predisposition to atopic dermatitis in this infant?

2. Explain why a secondary bacterial infection has probably developed?

3. List four factors that tend to aggravate atopic dermatitis?

4. Explain two ways in which administration of an antihistamine could help J.W. sleep?

Two years later, eczema has persisted, although controlled partially by use of moisturizers and hydrocortisone cream. The skin in some areas is thick and rough in texture.

5. Explain how hydrocortisone cream may reduce the inflammation and skin damage?

Explanation / Answer

1) The factors in the family history that support for genetic predisposition for atopic dermatitis include the history of atopy in the family like asthma, hayfever and allergic rhinoconjuctivitis.

2) Atopic dermatitis is a chronic, pruritic, eczematous skin condition. Secondary bacterial infection occurs more frequently because of disruption in the epidermal barrier function and the innate immune system.

3) Aggrevating factors of atopic eczema are,

4) Antihistamines are used to get relief from itching caused by release of histamines in atopic dermatitis. Apart from this, antihistamines ae also used to inhibit eosinophil migration and release of mediators.

5) Hydrocortisone cream moisturizes skin and helps to reduce the symptoms of atopic dermatitis.

Related Questions

Navigate

• Browse (All)
• Browse J
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.