The functional group changes in Rxn 6 of glycolysis are both important and also

Question

The functional group changes in Rxn 6 of glycolysis are both important and also a bit tricky to see. Which of the following best describes these changes (all of them).

A. An aldehyde is oxidized to a carboxylic acid and a phospho-ester is synthesized from that acid and Pi.

B. NADH is used to oxidize an aldehyde and a mixed anhydride is formed.

C. NAD+ is used to oxidize an aldehyde to a carboxylic acid; then a mixed anhydride is then formed between that acid and Pi.

D. NAD+ is oxidized by an aldehyde and a mixed anhydride then formed.

Explanation / Answer

C. NAD+ is used to oxidize an aldehyde to a carboxylic acid; then a mixed anhydride is then formed between that acid and Pi.

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