Police captain Jeffers had a myocardial infarction. He has an ejection fraction

Question

Police captain Jeffers had a myocardial infarction. He has an ejection fraction of only 25%. What type of treatment can be used to increase cardiac output for the police captain? SELECT ALL that apply. G beta-adrenergic blocker norepinephrine acetylcholine venous constriction (increase venous return) stimulating the cardio-inhibitory center thyroxine calcium channel blocker calcium channel activator An increase in stroke volume by the sympathetic nervous system is a: positive inotropic effect. negative inotropic effect.

Explanation / Answer

Mechanism: - Norepinephrine is the ligand that binds with the alpha, beta-adrenergic receptors. Alpha-1 get paired with Gq (activate phopholipase) that releases the calcium ion and cause smooth muscle movement. Alpha-2 subunit binds with the Gi subunit (inhibit the production of cAMP to ATP) which cause the neurotransmitter level down. This mechanism followed for the heart muscle contraction and relaxation.

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