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4:44 PM 4G www.chegg.com /homework-he L8 Your question has been answered! Rate it below. Let us know if you got a helpful answer. Question 50lv tnt f Component 3 Cem ent C Spotting line You spot an unknown analgesic drug on a TLC plate, develop the plate, then visualize it. The resulting TLC plate is shown above. The overall length of the plate is 10.0 cm. Your spotting line is 1.5 cm from the bottom of the plate. You mark the solvent front l.0 cm from the top of the plate. You measure the three spots and find that Component A traveled 6.3 cm, Component B traveled 4.0 cm, and Component C traveled 2.1 cm. Calculate the Ri value for each of the three components. 2. What are the two methods of visualization used in this TLC experiment? You have just run a TLCof a three component mixture, using a silica gel plate and an 80:20 mixture of chloroform and methanol (mobile phase). Your goal is to purify spot B (0.52 away from spots A (0.23) and C (0.81), with their Rfs given in parentheses. However, to purify a compound on TLC, you've been told that having an Rf of 0.3 of the spot to be purified isideal. Which solvent would you add more of in the mobile phase to achieve this?

Explanation / Answer

Solution :-

Given data

TLC plate length = 10 cm

Spotting line marked at 1.5 cm from bottom and run to 1 cm below the top of TLC plate

So the distance traveled by solvent = 10 cm

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