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Insulin is a peptide hormone secreted by the beta cells of the pancreas in respo

ID: 872621 • Letter: I

Question

Insulin is a peptide hormone secreted by the beta cells of the pancreas in response to elevated levels of blood glucose. Locally, insulin will inhibit the release of glucagon from alpha cells in the pancreas, and it will also impact the metabolism of many peripheral tissues. The actions of insulin are best described as which of the following?

a.

autocrine only

b.

paracrine and autocrine

c.

endocrine only

d.

Paracrine and endocrine

a.

autocrine only

b.

paracrine and autocrine

c.

endocrine only

d.

Paracrine and endocrine

Explanation / Answer

Pancreas is an Endocrine gland

Autocrine signaling is a form of signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine receptors on the same cell, leading to changes in the cells.

Paracrine signaling is a form of cell signaling in which the target cell is near the signal-releasing cell, altering the behavior or differentiation of those competent cells.

So, the answer is (d) Paracrine and endocrine

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