Describe the role of the malate aspartate shuttle (22.8) in moving cytosolic NAD

Question

Describe the role of the malate aspartate shuttle (22.8) in moving cytosolic NADH into the mitochondria and transporting aspartate out of the mitochondria

15: Describe the role of anaerobic glycolysis in the red blood cell

16: Determine the impact of glucagon, insulin, cortisol and epinephrine on the liver, skeletal muscle, and adipose tissue

17: Describe the roles and regulation of citrate synthase, isocitrate dehydrogenase, alpha-ketoglutarate dehydrogenase, and malate dehydrogenase in the TCA cycle

17: Describe the regulation of hexokinase/glucokinase, phosphofructokinase-1 (PFK-1), and pyruvate kinase in glycolysis

18: Describe the synthesis and release of insulin from beta cells

Explanation / Answer

15: Describe the role of anaerobic glycolysis in the red blood cell

Anaerobic glycolysis is the transformation of glucose into lactate in limited supply of oxygen. Due to the presence of haemoglobin in the red blood cells they lack mitochondria which produce energy for the cell. So red blood cells metabolize glucose mainly by anaerobic glycolysis which gives lactate as an end product, which then releases from the cell yeilding 2 ATP for each glucose molecule. In short anaerobic glycolysis provides energy to red blood cells.

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