Question 1 to 8. The Patient: Paramedics were called to the home of the Mathews

Question

Question 1 to 8.

The Patient: Paramedics were called to the home of the Mathews family because their 3-year old daughter, Molly, had gotten into the medicine cabinet and consumed a large number of aspirin tablets. When the paramedics arrived Molly had vomited several times, with bits of undissolved tablets visible, but seemed sleepy, almost lethargic. She was rushed to the nearest Emergency Room. When she reached the hospital she was unarousable and was breathing rapidly and deeply. She was examined and lab samples were obtained. Above is the structure of aspirin, or acetylsalicylic acid, which Is a weak add with a pKa of 3.5. The active, and toxic at high doses, form is the protonated form. What percent of the Ingested aspirin is in the active form In the stomach (remember that gastric Juice has a pH of ~1.5)? A. 0.0196 B. 1% C. 50 % D. 99% What percent of ingested and absorbed aspirin is in the active form in the blood (average pH of 7.4) under normal conditions? A. 0.00013% B. 0.013% C. 50% D. 100% Molly's lab analyses came back and she had a blood pH of 6.8. By what factor does the [H^+] of Molly's blood differ from normal blood? A. 0.25X B. 0.5 X C. 0.6X D. 2.0X e. 4.0X

Explanation / Answer

answers:

1) B

2) A

3) D

4) D

5) C

She is out of breath from all she has been through

6) C

Blood bicarbonate below normal.

7) B

Increase the rate of absorption of the asprin to shorten the duration of the overdose

8) B

shift towards right

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