We all know that carbohydrate cannot be synthesized from \"fat\" in the diet --

Question

We all know that carbohydrate cannot be synthesized from "fat" in the diet -- whereas, "fat" (triacylglycerols) certainly can be synthesized from carb (!).

More accurately, carbohydrates such as glucose cannot be synthesized from fatty acids.

Why is this statement true? This is discussed explicitly in your text.

A. AcetylCoA from beta-oxidation cannot enter the citric acid cycle.

B. NADH from beta-oxidation could not be used as reducing power in gluconeogenesis.

C. The synthesis of aceylCoA from pyruvate is metabolically irreversible -- thus, pyruvate cannot be synthesized from acetylCoA and CO2.

D. All of the above are reasons why glucose cannot be synthesized from fatty acids.

Explanation / Answer

D. All of the above are reasons why glucose cannot be synthesized from fatty acids.

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