Which would be the best example of a \"tightly linked\" RFLP? An RFLP caused by
ID: 85980 • Letter: W
Question
Which would be the best example of a "tightly linked" RFLP?
An RFLP caused by a base substitution that confers the sickle allele and also changes the restriction site in the hemoglobin gene.
An RFLP that is 2 map units away from the gene that confers cystic fibrosis when mutant.
An RFLP that almost always assorts independently from a gene of interest.
An RFLP that is linked very closely to the gene that causes achondroplasia with a recombination frequency of 0.015.
AAn RFLP caused by a base substitution that confers the sickle allele and also changes the restriction site in the hemoglobin gene.
BAn RFLP that is 2 map units away from the gene that confers cystic fibrosis when mutant.
CAn RFLP that almost always assorts independently from a gene of interest.
DAn RFLP that is linked very closely to the gene that causes achondroplasia with a recombination frequency of 0.015.
Explanation / Answer
Restriction Fragment Length Polymorphism subtraction methods are very useful determining also applicable to positional cloning method that unusually requires a genetic map. RFLP markers spanning an entire genome is useful in the method Targeted RFLP Subtraction (TRS).
Here the answer will be: B. An RFLP that is 2 map units away from the gene that confers cystic fibrosis when mutant. Here the linked RFLP markers are very useful determining genes from the genes that a particular organism or a condition possess.
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