Of the following human aneuploidles, which is the one that generally has the mos

Question

Of the following human aneuploidles, which is the one that generally has the most severe impact on the health of the individual? A) 47, +21 B) 47, XXY C) 47, XXX D) 47, XYY E) 45, X What is the role of DNA ligase in the elongation of the lagging strand during DNA replication? A) It synthesizes RNA nucleotides to make a primer. B) it catalyzes the lengthening of telomeres. C) it joins okazaki fragments together. D) it unwinds the parental double helix. E) it stabilizes the unwound parental DNA. A new DNA strand elongates only in the 5' to 3' direction because A) DNA polymerase begins adding nucleotides at the 5' end of the template. B) Okazaki fragments prevent elongation in the 3' to 5' direction. C) the polarity of the DNA molecule prevents addition of nucleotides at the 3' end. D) replication must progress toward the replication fork. E) DNA polymerase can only add nucleotides to the free 3' end. Why do histones bind tightly to DNA? A) Histones are positively charged, and DNA is negatively charged. B) Histones are negatively charged. and DNA is positively charged. C) Both histones and DNA are strongly hydrophobic. D) Histones are covalently linked to the DNA E) Histones are highly hydrophobic, and DNA is hydrophilic. Which of the following nucleotide triplets best represents a codon? A) a triplet separated spatially from other triplets B) a triplet that has no corresponding amino acid C) a triplet at the opposite end of tRNA from the attachment site of the ammo acid D) a triplet in the same reading frame as an upstream AUG E) a sequence in tRNA at the 3' end 39) A part of the promoter, called the TATA box, is said to be highly conserved in evolution. which of the following might this illustrate? A) The sequence evolves very rapidly. B) The sequence does not mutate. C) Any mutation in the sequence is selected against. D) The sequence is found in many but not all E) The sequence is transcribed at the start of every gene.

Explanation / Answer

34)A) 47, +21

35)C) It joins Okazaki fragments together.

36)E) DNA polymerase can only add nucleotides to the free 3' end

37)A) Histones are positively charged, and DNA is negatively charged.

38)D) a triplet in the same reading frame as an upstream AUG

39)C) Any mutation in the sequence is selected against.

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