Which of the following DNA mutations is the most likely to be damaging to the pr

Question

Which of the following DNA mutations is the most likely to be damaging to the protein it specifies? A) a base-pair deletion B) a substation in the last base of a codon C) a codon substitution D) a point mutation E) a codon deletion chromosome. Sex determination in mammals is due to the SRY region of the Y chromosome. An abnormality of this region could allow which of the following to have a male phenotype? A) Turner syndrome, 45, X B) translocation of SRY to an autosome of a 46, XX individual C) a person with an extra X chromosome D) a person with one normal and one shortened (deleted) X E) Down syndrome, 46, XX

Explanation / Answer

ANSWERS:

49)A) a base-pair deletion

An error in the repair of damaged DNA.

50)B) translocation of SRY to an autosome of a 46, XX individual .

The SRY gene is found on the Y chromosome. The sex-determining region Y protein produced from this gene acts as a transcription factor, which means it attaches to specific regions of DNA and helps control the activity of particular genes.

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