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Which of the following is TRUE? Defective DNA repair enzymes can produce tumors

ID: 84991 • Letter: W

Question

Which of the following is TRUE? Defective DNA repair enzymes can produce tumors Unregulated transcription factors can produce tumors A normal Ras protein produces tumors. Mutations in p53 prevent apoptosis. Which of the following is FALSE? Modified retroviruses can be used to introduce genes into humans. DNA chips can carry sequences from over 1000 genes on chip. It currently takes years to sequence a human genome. ASO's can be used to test for inherited disease. Transgenic plants: are cultivated in the USA can be made using Ti and plant tissue culture may be resistant to insect pests all the above are true The restriction endonucleases used in recombinant DNA work MAY produce sticky ends recognize sequences 14-16 bp long cut the DNA 15 bp away from the recognition sequence all the above Which of the following is TRUE about current Sanger dideoxy sequencing procedures? Chain termination occurs during synthesis of a new DNA strand. A radioactive label is a

Explanation / Answer

Answer:

40. (c) A normal Ras protein produces tumors

When Ras is 'switched on' by incoming signals, it subsequently switches on other proteins, which ultimately turn on genes involved in cell growth, differentiation and survival. Mutations in ras genes can lead to the production of permanently activated Ras proteins. As a result, this can cause unintended and overactive signaling inside the cell, even in the absence of incoming signals.

41. (c) It currently takes years to sequence a human genome

Sequencing the first human genome cost about $1 billion and took 13 years to complete; today it costs about $3,000 to $5000 and takes just one to two days.

42. (d) All the above are true

43. (a) May produce sticky ends

(Since there are more than 1 question, the first 4 questions have been answered according to the rules of Chegg)

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