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mutation typically involves a single base substitution at the ___ position of th

ID: 84819 • Letter: M

Question

mutation typically involves a single base substitution at the ___ position of the codon, whereas a mutation typically involves a single base substitution at the ___ ribonucleoside position of a codon. A) 1st or 2nd; 3rd B) 3rd; 1st or 2nd C) 2nd or 3rd; 1st D) 1st; 2nd E) 3rd: 1st ___ of genes are alternatively spliced in humans. A) very few B) Less than half C) More than half D) None In eukaryotic pre mRNAs, sequences which do not encode for amino acids (untranslated sequences) are found ___ A) at the 5' end of the transcript B) at the 3' end of the transcript C) between coding of the protein-coding region of the pre-mRNA D) A and C only E) A, B, and C Given that the top strand of the following double stranded DNA sequence is the template/antisense strand, what is the corresponding mRNA sequence? 5'-GAGCT =3' (template; antisense) 3'-CTCGA-5' A) 5;-GAGCU-3 B) 5-AGCUC-3 C) 5-AGCTC-3' D) 5-AGCTC-3' E) 5'-CUCGA-3' The initiating fMet-tRNA/Met pairs with its corresponding codon on the mRNA at the ___ site of the ribosomal complex. The anticodon of each subsequent aminoacyl tRNA pairs with its corresponding codon on the mRNA at the ___ site of the ribosomal complex and, following peptide bond formations, the free tRNA is released from the ___ site of the ribosomal complex. A)A; E: P B) P; A; E C) A; P; E D) E; P: A Interactions between the side groups of amino acids within a polypeptide allow for folding of the polypeptide into a structure. ___ A) primary B) secondary C) tertiary D) quaternary E) none of the above "Wobble", or noncomplementary pairing of ribonucleosides, occurs at the ___ ribonucleoside position of the codon in mRNA, which corresponds to the ___ ribonucleoside position of the anticodon of the tRNA. A) first; third B) second; first C) third, first D) fourth; second E) none of the above On the planet Arakis, there are 25 unique amino acids instead of 20 and there are only 2 unique ribonucleosides instead of 4. What is the minimal number of nucleosides per codon on Arakis? A) 4 B) 5 C) 6 D) 7 E) none of the above Peptide bonds result from a dehydration reaction between the ___ group of the first amino acid and the ___ group of the next amino acid. A) amino; carboxyl B) carboxyl; amino C) amino; hydroxyl D) hydroxyl; amino A ___ mutation changes the sequence of the codon and changes the amino acid coding of a codon, but results in no but structural or functional consequence in the polypeptide/protein; a ___ mutation changes the sequence of the codon, but does not alter the amino acid coding. A) nonsense; missense B) neutral; silent C) missense; nonsense D) silent; neutral E) none of the above Which of the following sequences is used as a translational start codon in mRNA? a) AUC B) AUT C) ATG D) AUG E) none of the above

Explanation / Answer

59:

Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. There are more than 90 percent of human genes undergo alternative splicing.

Hence the correct option is C