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Purine biosynthesis starts with the activation of a 5 carbon sugar. In this init

ID: 841334 • Letter: P

Question

Purine biosynthesis starts with the activation of a 5 carbon sugar. In this initial reaction, ribose 5-phosphate is converted into which of the following compounds?

PRPP (5- phosphoribosylpyrophosphate)

inosine monophosphate

glucose 6-phoshate

5- methyl thymidine

The regulation of PRPP synthetase is critical in the production of both purines and pyrimidines. This enzyme is inhibited under which of the following conditions?

When both GDP and ADP are elevated

When IMP is elevated

When CDP and TDP are elevated

When IMP is elevated

PRPP (5- phosphoribosylpyrophosphate)

inosine monophosphate

glucose 6-phoshate

5- methyl thymidine

The regulation of PRPP synthetase is critical in the production of both purines and pyrimidines. This enzyme is inhibited under which of the following conditions?

When both GDP and ADP are elevated

When IMP is elevated

When CDP and TDP are elevated

When IMP is elevated

Explanation / Answer

PRPP (5- phosphoribosylpyrophosphate)

When both GTP and ATP are elevated

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