I JUST NEED NUMBER 7 (a through d) a. Describe this sensing mechanism. b. How do
ID: 84098 • Letter: I
Question
I JUST NEED NUMBER 7 (a through d)
a. Describe this sensing mechanism. b. How does oxygen binding affect the behavior of globin/hemoglobin? How do the mechanisms of action of serine proteases and aspartyl proteases differ? Explain in detail, including the identities/structures of all critical amino acids in a diagram. Consider the action of a suicide inhibitor of chymotrypsin, like DIPF. Assuming the active site could accommodate DIPF, would it also irreversibly inhibit the aspartyl proteases? Why or why not? One indication of the relative importance of various ATP-producing pathways is the Vmax of certain enzymes of these pathways. The values of Vmax of several enzymes from the pectoral muscles (chest muscles used for flying) of pigeon and pheasant are listed below. a. Discuss the relative importance of metabolism and fat metabolism in generating ATP in the pectoral muscles of these birds. b. Compare oxygen consumption in the two birds. C. Judging from the data in the table, which bird is the long-distance flyer? Justify your answer. d. Why were these particular enzymes selected for comparison? Would activities of triose phosphate isomerase and malate dehydrogenase be equally good bases for comparison? Explain. The Citric Acid Cycle a. Briefly describe the relationship of the pyruvate dehydrogenase complex reaction to glycolysis and the citric acid cycle. b. Two of the steps in the oxidative decarboxylation of pyruvate to acetyl-CoA do not involve the three carbons of pyruvate, yet are essential to the operation of the pyruvate dehydrogenase complex. Explain. c. Describe THREE essential cofactors (NOT NAD+ and FAD) which are required for the successful oxidation of pyruvate to carbon dioxide. What are their roles? What do they contribute to the reactions in which they are involved?Explanation / Answer
(a) In pectoral muscles of pigeon the fatty acid catabolism is primary pathway whereas in Pheasant the glycolysis (anaerobic) is of primary importance in form of ATP producing pathways.
(b) Oxygen consumption is higher in Pigeon muscles than those of Pheasant.
(c) Pigeon is dependent on fat oxidation and fat produces more energy for flying than glycogen, so pigeon will be log distance flyer.
(d) All the listed enzymes have predominant regulatory role in ATP production and their activities affect other processes as well.
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