The doctors showed Jane an impressive array of assessment tools for quantifying

Question

The doctors showed Jane an impressive array of assessment tools for quantifying and analyzing her physiological state before, during, and after his workouts. One of the tools was urinalysis, which Jane found a bit odd, but she dutifully supplied urine samples on a regular, prescribed basis. The researchers explained that Jane's renal status (as measured in the urinalysis) was one of the tools she could use to evaluate her physiological state. Jane also received 2 L of 0.5% NaCl + 250 ng/L of Drug X immediately after exercise over 15 minutes. The following results of Jane's urinalysis and blood analysis immediately after, 3 hours after and six hours after, a rigorous 2-hour run. Jane's weight = 55 kg. Renal Blood Flow = 1200 mL/min. Jane produced 750 mL in 6 hours. Based on this information, calculate the volumes and osmolarity of the intracellular and extracellular fluid immediately after exercise and 6 hours later after IV treatment of NaCI + X.

Explanation / Answer

Approximately 67% of total body water is in the intracellular fluid (ICF) compartment there fore 67% of 750 mL

Osmolarity is calulated in 2 steps:
for 0.5% NaCl
Molarity of NaCl = (0.5/100ml) / (molecular weight of NaCl)= 0.000086
Osmolarity = 2 * Molarity of NaCl = 2* 0.000086= 0.000172

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