8. All of the following statements about the enzymic complex that carries out th

Question

8. All of the following statements about the enzymic complex that carries out the synthesis of ATP during oxidative phosphorylation are correct EXCEPT: a). It is located on the matrix side of the inner mitochondrial membrane. b). It is inhibited by oligomycin. c). It contains a proton channel. d). It can exhibit ATPase activity. e). It can bind molecular oxygen.

9. What is the terminal component in the electron transport chain that reduces oxygen to form water and that can be poisoned by cyanide? a. cytochrome c1 b. cytochrome oxidase c. cytochrome c d. cytochrome e e. cytochrome b

10. An uncoupler of oxidative phosphorylation such as dinitrophenol: A. inhibits electron transport and ATP synthesis. B. allows electron transport to proceed without ATP synthesis. C. inhibits electron transport without impairment of ATP synthesis. D. specifically inhibits cylochrome b. E. acts as a competitive inhibitor of NAD+-requiring reactions in the mitochondrion.

Explanation / Answer

8. ATP synthase cannot bind to oxygen.

So the answer is: e). It can bind molecular oxygen.

9. Cyanide inhibits Complex IV that is cytochrome oxidase.

So the answer is: b. cytochrome oxidase

10. Uncouplers disruots the proton gradient thus inhibiting synthesis of ATP. It will not have any effect on the ETC.

So the answer is: B. allows electron transport to proceed without ATP synthesis.

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