Kinetic constants for inhibition studies on enzymes are described below. For eac

Question

Kinetic constants for inhibition studies on enzymes are described below. For each part a-h: determine if the numerical values for the constants are identical or different (increased or decreased). Km values in the absence and presence of a competitive inhibitor. values in the absence and presence of a competitive inhibitor. Km values in the absence and presence of a noncompetitive inhibitor. Vmax values in the absence and presence of a noncompetitive inhibitor. Km values in the absence and presence of an uncompetitive inhibitor. Vmax values in the absence and presence of an uncompetitive inhibitor. How slope would be affected by the presence of noncompetitive inhibitor in a Lineweaver-Burk plot How the y-intercept would will be affected by the presence of noncompetitive inhibitor.

Explanation / Answer

1. a) increased

b) identical

c) identical

d) decreased

e) decreased

f) decreased

g) decreased

h) identical

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