Proto-oncogene in normal situation regulates: A) Stimulation of cell cycle progr
ID: 82637 • Letter: P
Question
Proto-oncogene in normal situation regulates: A) Stimulation of cell cycle progression B) inhibits cell cycle C) loss/inactivating mutation causes cancer D) None of the above Which of the following statement about enhancers is correct? A) They contain unique base sequence which are upstream (-35) of starting base B) They are located only in 3 flanking regions of the telomere C) They are located only in proteins synthesizing transitional machinery D) They are present at -2000 or in a variety of upstream locations and are involve m activating transcription If changes in gene expression are independent of DNA sequence (epigenetic); then which of the following is an example of an epigenetic change(s) in eukaryotic transcription regulation? A) Methylation DNA B) Amplification of DNA C) Transition type of mutation D) Transversion type of DNA Pay attention to the following, which may described the best in questions 1S-19: A. enhancer B. promoter C. activator D. repressor E. terminator Can inhibit transcription by blocking of positively acting transcription factors the DNA. Site in the DNA that may be located far from that transcription initiation siteExplanation / Answer
12. (A) proto oncogenes normally regulate the stimulation of cell cycle or cell division. If mutation occur in proto oncogenes then it converts into oncogenes and cause the cancer.
13. (D) They are present at -2000 or in a variety of upstream locations and are involve in activating transcription. Enhancer is short DNA region that can be bound to proteins (activator) to increase the transcription of a gene.
14. (A) Methylation of DNA .
Transcription can be regulate or silenced by DNA methylation, RNA interference and histone modification.
15. If repressor bind to promotor then transcription will inhibit, also after binding of transcription factors to the DNA.
16. Terminator sequence is located far from the transcription initiation site. This termination seqeunce stop the trascription.
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