1) Which of the following is(are) involved in intermolecular attractions between

Question

1) Which of the following is(are) involved in intermolecular attractions between a drug and a protein receptor?

Hydrogen bonds.

nonpolar hydrophobic interactions

Ionic bonds.

ion-dipole interactions

all of the above.

2) The surface of a particular active site contains many amino acids with nonpolar side chains. Which functional group(s) will be more effective on the active part of a drug molecule designed to inhibit this enzyme?

alcohol

ester

carboxylic acid.

aromatic and alkyl

alkyl only

3) The surface of a particular active site contains an amino acid with a positively charged side chain. Which functional group(s) will be more effective on theactive part of a drug molecule designed to inhibit this enzyme?

-OH

-C3H7

-CH=CH2

-COO?

-NH3+

Hydrogen bonds.

nonpolar hydrophobic interactions

Ionic bonds.

ion-dipole interactions

all of the above.

Explanation / Answer

1. ALL OF THE ABOVE

2. AROMATIC & ALKYL

3. coo-

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