The ? oxidation pathway degrades activated fatty acids (acyl-CoA) to acetyl-CoA,

Question

The ? oxidation pathway degrades activated fatty acids (acyl-CoA) to acetyl-CoA, which then enters the citric acid cycle. Additional enzymes are required to oxidize unsaturated, odd-chain, long-chain, and branched fatty acids. Which of the following statements are true?

1.Trans double bonds in unsaturated fatty acids are not recognized by ? oxidation enzymes.

2.Enoyl-CoA isomerase, an enzyme that converts cis double bonds to trans double bonds in fatty acid metabolism, bypasses a step that reduces Q, resulting in a higher ATP yield.

3.A 14-carbon monounsaturated fatty acid with cis configuration yields more ATP than a 14-carbon saturated fatty acid.

4.Complete catabolism of the three-carbon remnant of a 15-carbon fatty acid requires some citric acid cycle enzymes.

5.The final round of ? oxidation for a 13-carbon saturated fatty acid yields acetyl-CoA and propionyl-CoA, a three-carbon fragment.

6.Even-chain saturated fatty acids are oxidized to acetyl-CoA in the ? oxidation pathway.

Explanation / Answer

4, 5, 6 is the answer

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