The typical reaction of carboxylic acid derivatives* (CAD) is __________________
ID: 813298 • Letter: T
Question
The typical reaction of carboxylic acid derivatives* (CAD) is ________________________ The typical reaction of aldehydes and ketones is ____________________________ Why is there a difference? What are the relative reactivities of CADs? Explain the trends. Which CADs can be interconverted? How doe you prepare each type of CAD from a carboxylic acid? Note there may be several ways for some of them. What is the hydrolysis product of all CADs and nitrile? What conditions are involved? Be able to show the mechanism of each reaction. (Hint: all lead to the same functional group) What is the alcoholysis product of -COOH, acid halide and anhydride? Again what are the conditions and know the mechanism.Explanation / Answer
1. electrophilic substitution at oxygen
2. Nucleophilic addition
3. Due to acidic hydrogen
4. acyl halides > anhydrides >> esters ? acids >> amides
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