This is a very simpllistic approach to protein folding, which ignores solvent an

Question

This is a very simpllistic approach to protein folding, which ignores solvent and volume effects, but it allows us to practice what we have learned about thermodynamics and kinetics. Enzymes are long chains of amino acids that have to fold in the proper way so as to exhibit enzyme activity. They can catalyze certain reactions. Let us pick a reaction in the human body at 37 C, we will call it enzyme X.

Under what conditions is the folded form NOT thermodynamically favored? (high temp, low temp, always, or never favored)

Explanation / Answer

All biological reactions occur at ambient temperature (25oC) only spontaneously. Thus all enzymes which are in native form, that is in folded state get denatured at a temperature beyond 40oc. Thus folded form is not thermodynamically favoured at high temperatures.

Related Questions

Navigate

• Browse (All)
• Browse T
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.