True False During pregnancy IgG antibodies and activated lymphocytes can cross t

Question

True

False

During pregnancy IgG antibodies and activated lymphocytes can cross the placenta and enter the circulatory system of the fetus.

True

False

Blood plasma exchange (plasmapheresis) can be used to remove maternal IgG form the newborn

True

False

All autoimmune diseases involve a breach of T-cell tolerance

True

False

Newborns of mothers with T cell-mediated autoimmune diseases exhibit the same symptoms as their mothers.

True

False

Autoimmune diseases can be induced after an infection.

True

False

Graft-versus host disease occurs when transplanted bone marrow contains mature T cells which attack the host.

True

False

SLE is an example of intermolecular spreading.

True

False

The NOD mouse model is used for studying diabetes.

True

False

During pregnancy IgG antibodies and activated lymphocytes can cross the placenta and enter the circulatory system of the fetus.

True

False

Blood plasma exchange (plasmapheresis) can be used to remove maternal IgG form the newborn

True

False

All autoimmune diseases involve a breach of T-cell tolerance

True

False

Newborns of mothers with T cell-mediated autoimmune diseases exhibit the same symptoms as their mothers.

True

False

Autoimmune diseases can be induced after an infection.

True

False

Graft-versus host disease occurs when transplanted bone marrow contains mature T cells which attack the host.

True

False

SLE is an example of intermolecular spreading.

True

False

The NOD mouse model is used for studying diabetes.

Explanation / Answer

Mothers system does not continuous with fetus therefore activated lymphocyte cannot cross the placenta. But IgG can cross it.

Plasmapheresis is process replacing of plasma that can affect its own system. This technique is use for myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, guillain-Barre syndrome etc

Some auto immune diseases cause by the T-cells. But auto antibodies cause auto immune disease Myasthenia gravis.

Because T-cells do not cross the placenta.

Molecular mimicry of some antigens is lead to immune response against some proteins of our body.

In transplant mature T-cells are present in graft that leads to immune response.

Anti n-RNP autoantibodies attacks on prolin-rich motifs.

NOD (non-obese diabetic) mice leads used for type I diabetes study.

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