“One of the great kings of the past ruled an enormous kingdom that was more beau
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Question
“One of the great kings of the past ruled an enormous kingdom that was more beautiful than anywhere else in the world. Every plant glistened as brilliantly as polished jade, and the softly rolling hills are as sleek as the waves of the summer sea. The wisdom of all of his decisions relied on a constant flow of information brought to him daily by messengers who told him about every detail of his kingdom so that he could take quick appropriate actions when needed. Despite the abundance of beauty and efficiency, his people felt doomed living under his rule, for he had an adviser who had studied cell signal transduction and accordingly administered the King’s Department of Information. The adviser had implemented the policy that all messengers shall be immediately beheaded whenever spotted by the Royal Guard, because for rapid signaling the lifetime of messengers ought to be short. Their plea “Don’t hurt me, I’m only the messenger!: was to no avail, and the people of the kingdom suffered terribly because of the rapid loss of their sons and daughters.” Why is the analogy on which the king’s adviser based his policies inappropriate? Briefly discuss the feature that set cell signaling pathways apart from the human communication pathway described in the story.Explanation / Answer
In cell signalling pathways, the ligand binds to the receptor and triggers this signalling pathway. if the molecule is not destroyed, it will continue to bind and continuously trigger these pathways. this would make the cell cancerous. to prevent this the messenger is destroyed. in the human communication described in this story,the messengers are human and usually will not tell the same message to the same person twice. hence they can be spared.
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