A. Please describe how the cytoskeleton plays a role in chromosome segregation d

Question

A.      Please describe how the cytoskeleton plays a role in chromosome segregation during mitosis.

B.       Please describe how the cytoskeleton plays a role in cytokinesis.

C.       You have found an unlabeled bottle which you believe contains either nocodazole (a drug which inhibits microtubule polymerization) or cytochalasin D (a drug which destabilizes actin filaments). To identify which drug it is, you add an aliquot to a culture of cells. You find that under treatment with this drug, cells are able to undergo mitosis, but a binucleate cell (a cell containing two nuclei) is generated. Which drug is in the bottle? Please provide a reason for your prediction.

Explanation / Answer

A answer.  

B Answer.

C Answer.

Based on the above observation the drug present in the unlabelled bottle is identified as Cytocephalin D in a cell culture test in which we could see nuclear division but not cytokinesis.

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