1.) what hematology test may be abnormal in selenium toxicity and state their si
ID: 80300 • Letter: 1
Question
1.) what hematology test may be abnormal in selenium toxicity and state their significance in the disease process? 2.) explain why abnormal heart rhythm and hypotension are commonly associated with chronic intoxication of selenium? 3.) discuss why cramps, edema and pain in the extremities are commonly observed in patient with selenium toxicity? 4.) what is the best type of sample to submit for this type of toxicity and why? 1.) what hematology test may be abnormal in selenium toxicity and state their significance in the disease process? 2.) explain why abnormal heart rhythm and hypotension are commonly associated with chronic intoxication of selenium? 3.) discuss why cramps, edema and pain in the extremities are commonly observed in patient with selenium toxicity? 4.) what is the best type of sample to submit for this type of toxicity and why? 2.) explain why abnormal heart rhythm and hypotension are commonly associated with chronic intoxication of selenium? 3.) discuss why cramps, edema and pain in the extremities are commonly observed in patient with selenium toxicity? 4.) what is the best type of sample to submit for this type of toxicity and why?Explanation / Answer
1) The hematology test done to diagnose selenium toxicity is called as Se Serum blood test. In this hematology test selenium is measured along with other trace elements like iron, zinc and copper. Serum/ plasma selenium concentration can can decrease during the acute phase response to illness or trauma. Functional selenium deficiencies are assessed by measurement of enzyme activity of selenium dependent proteins like glutathione peroxidase which correlates with longer term selenium status.
2. Patients with selenium toxicity result in decreased levels of calcium absorption leading to cramps, edema and pain.
3. Blood sample as measurement of selenium in the plasma/ Serum can be done from it. The blood sample may be taken from a vein in the arm.
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