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The picture below shows HCV NS3 protease inhibitors that are recently approved d

ID: 800214 • Letter: T

Question

The picture below shows HCV NS3 protease inhibitors that are recently approved drugs for treating HCV infection, and other inhibitors currently in phase III clinical trials (Steven R. LaPlante, et. al. J. Med. Chem., Article ASAP DOI: 10.1021/jm401338c). Identify which compound has the greatest number of chiral centers:

The picture below shows HCV NS3 protease inhibitors that are recently approved drugs for treating HCV infection, and other inhibitors currently in phase III clinical trials (Steven R. LaPlante, et. al. J. Med. Chem., Article ASAP DOI: 10.1021/jm401338c). Identify which compound has the greatest number of chiral centers:

Explanation / Answer

Answer is Telaprevir 6 chiral centers

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