As a technician in a large pharmaceutical research firm, you need to produce 250
ID: 799042 • Letter: A
Question
As a technician in a large pharmaceutical research firm, you need to produce 250.mL of 1.00 M a phosphate buffer solution of pH = 7.38. The pKa of H2PO4? is 7.21. You have 2.00 L of 1.00 M KH2PO4 solution and 1.50 L of 1.00 M K2HPO4 solution, as well as a carboy of pure distilled H2O. How much 1.00 M KH2PO4 will you need to make this solution? Express your answer numerically in milliliters to three significant figures As a technician in a large pharmaceutical research firm, you need to produce 250.mL of 1.00 M a phosphate buffer solution of pH = 7.38. The pKa of H2PO4? is 7.21. You have 2.00 L of 1.00 M KH2PO4 solution and 1.50 L of 1.00 M K2HPO4 solution, as well as a carboy of pure distilled H2O. How much 1.00 M KH2PO4 will you need to make this solution? Express your answer numerically in milliliters to three significant figuresExplanation / Answer
pH = pKa + log [anion] / [acid]
7.43 = 7.21 + log [anion] / [acid]
0.22 =log [anion] / [acid]
10 to the x of both sides
1.6596 = [anion] / [acid]
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