There are three RNA polymerases in eukaryotic cells, designated I, II, and III.

Question

There are three RNA polymerases in eukaryotic cells, designated I, II, and III. They differ in their functions, and they can be distiguished experimentally by their sensitivity to ?-amanitin, a poison from the mushroom Amanita phalloides. Match each polymerase to its function and ?-amanitin sensitivity.

There are three RNA polymerases in eukaryotic cells, designated I, II, and III. They differ in their functions, and they can be distinguished experimentally by their sensitivity to alpha-amanitin, a poison from the mushroom Amanita phalloides. Match each polymerase to its function and alpha -amanitin sensitivity. Function: Synthesizes mRNA. Synthesizes pre-ribosomal RNA. Synthesizes tRNA and small RNA's. Inhibition by alpha-amanitin: Not inhibited. Inhibited by high concentrations. Inhibited by low concentrations.

Explanation / Answer

RNA Polymerase I synthesizes pre-ribosomal RNA and is not inhibited by alpha-amaritin.

RNA Polymerase II synthesizes pre-mRNA and is inhibited by low concentrations of alpha-amaritin.

RNA Polymerase III synthesizes tRNA and small RNA's and is inhibited by high concentrations of alpha-amaritin.

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