C Chegg Save up to 9ON on x php? attempt 175002&page; 1 Latoya Blanks cel Biolog

Question

C Chegg Save up to 9ON on x php? attempt 175002&page; 1 Latoya Blanks cel Biology Lecture/Lab May-7 May Final Exam You are interested in studying the transerptional regulation of the Gip1 promoter The Gp1 promoter contains a binding site for the Jid protein that overlaps with the binding ste for the Pa5 protein JkB and Pa5 cannot bind DNA at the same time, but both proteins are present at high levels in adult iver oels The binding stes for Jk8 and Pa5 are shown in Figure Q8-33. JkB binds to site A while Pas binds to site B. You create mutations that remove the nonoverlapping sequences of either binding site A or B, and examine Gp1 mRNA production in adut liver cells that contain these mutations. The data you obtain from these experiments are shown in Table QB 33. experiment binding site Gipt mRNA Table 08-33 You know that Gopt is only expressed n adut iver oels and not inthe liver ofembryos You also know that Jk8 and Pa5 behave or other embno in of whether they act as actvators Gven the data, use of which of the following mechanisms would make the most sense for regulating the Jk8 and Pas proteins MacBook Air

Explanation / Answer

From the given table we can conclude that the GiP1 is only expressed only when there is an expression of Jk8. Also, it is given that Gip1 is not expressed in the embryonic cells. all these clues give us the hint that the Jk8 is not expressed on the embryonic cells.

So the answer is option D - Pa5 binds to the promoters of the genes that encodes Jk8 in the embryotic cells

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