In rabbits coat color is controlled by a single gene with 4 alleles: c^C>c^ch>c^

Question

In rabbits coat color is controlled by a single gene with 4 alleles: c^C>c^ch>c^h>c. c^C = full color, c^ch= chinchilla, c^h= Himalayan, c= colorless (albino rabbits). The Himalayan allele which results in a black nose, ears and paws is only functional below 30 degrees Celsius. At higher temperatures the protein doesn't function and the rabbits are albino. You cross two Himalayan rabbits. When you raise the progeny at 32 degrees Celsius, you get all albino bunnies. If you raise them at 25 degrees Celsius you get a 3:1 ratio of Himalayan to albino bunnies. What were the genotypes of the two parents? c^h c^h times c^h c^h c^h c times c^h c^h c^h c^h times cc c^h c times c^h c

Explanation / Answer

Both the parents will have genotype chc.

Parents                        chc (Himalayan) x                    chc (Himalayan)

Gametes                    ch, c                                                                            ch, c

Progeny         

chch

Himalayan

chc

Himalayan

chc

Himalayan

cc

Albino

So, the phenotypic ratio of the progeny is 3 himalayan: 1 albino (at 25 OC). Since the himalayan gene protein is non-functional above 30 OC, so all will appear albino at 32 OC.

Gametes ch c ch

chch

Himalayan

chc

Himalayan

c

chc

Himalayan

cc

Albino

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