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Red-green color blindness is an X-linked trait. In a population genetics study,

ID: 78067 • Letter: R

Question

Red-green color blindness is an X-linked trait. In a population genetics study, 1,000 people (500 men and 500 women) were tested for this trait, and 35 men were found to be color blind. Use this information to compute the frequency of the allele for color blindness and the wild-type allele in this population, and estimate the expected number of carrier females.

I'm assuming that the frequency of the recessive allele (q) is 35/500 which is 0.07

From that I used the p + q = 1 eqation to find that the frequency of p to be 0.93

Am i thinking through this correctly?????? If so, then where do I go from there?????

Explanation / Answer

yes you are proceeding correctly. the inheritance of the genotypes and their frequency will be the same in X linked traits as for any other autosomal dominant/ recessive trait we see but the phenotype calculation will be a bit different since all males who inherit the Xc will be colour blind but the women with one will be just carriers.

But since it is the same population, for women too p=0.93 q=0.07

the carriers females will be XcX= heterozygous= 2pq= 2*0.07*0.93.

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