AIDS drugs such as Indavir and Amprenavir act by 1. inhibiting an enzyme that ca

Question

AIDS drugs such as Indavir and Amprenavir act by 1. inhibiting an enzyme that catalyzes the cleavage of a peptide bond between the gag and pol fragments in the gag-pol protein.2 2.catalyzing the cleavage of a peptide bond between the gag and pol fragments of the gag-pol protein. 3. promoting the destruction of HIV protease. 4. inhibiting an enzyme that catalyzes the cleavage of the peptide bond to the terminal amino acid in the gag-pol protein. 5. binding to the gag-pol protein thus protecting the peptide bond between the gag and pol fragments.

Explanation / Answer

Indinavir is an antiretroviral protease inhibitor that acts by binding to the catalytic site of the HIV protease thereby preventing the cleavage of viral polyprotein precursors into mature, functional proteins that are necessary for viral replication. hece the correct answer is (A)

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