why doesn Solution glycogen synthase use glucose-1-phosphate. ->?glucose-1-phosp

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glycogen synthase use glucose-1-phosphate. ->?glucose-1-phosphate is formed upon breakdown, providing an activated sugar for possible synthesis reactions. glycogen phosphorylase is not involved in synthesis of glycogen (glycogen + Pi ---> G 1-P --x--> glycogen + Pi). 1-> ratio of [ Pi ]/[ glucose-1-phosphate ] is approximately 100 in the cell; this ratio does not favor synthesis of glycogen. 2-> patients with no muscle phosphorylase can make glycogen.. but using udp-glucose. 1-> UDP-glucose adds sequentially to the C-4 hydroxyl group (not the reducing end of the sugar) to produce a linear polymer of glucose..

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