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what specific information would you include in medication teaching? A. Dopamine

ID: 74837 • Letter: W

Question

what specific information would you include in medication teaching?

A. Dopamine D2 (as with use of antipsychotic drugs)

B. Blockage of muscarinic receptors (as with use of phenothiazines and other drugs)

C. 1 receptors (as with use of phenothiazines and other drugs)

D. Histamine (as with use of phenothiazines and other

drugs)

E. Monoamine oxidase (MAO) (as with use of a monoamine oxidase inhibitor [MAOI])

F. -Aminobutyric acid (GABA) (as with the use of

benzodiazepines)

G. Serotonin (as with the use of selective serotonin reuptake inhibitors [SSRIs] and other drugs)

H. Norepinephrine (as with the use of serotonin-norepinephrine reuptake inhibitors [SNRIs])

what specific information would you include in medication teaching?

A. Dopamine D2 (as with use of antipsychotic drugs)

B. Blockage of muscarinic receptors (as with use of phenothiazines and other drugs)

C. 1 receptors (as with use of phenothiazines and other drugs)

D. Histamine (as with use of phenothiazines and other

drugs)

E. Monoamine oxidase (MAO) (as with use of a monoamine oxidase inhibitor [MAOI])

F. -Aminobutyric acid (GABA) (as with the use of

benzodiazepines)

G. Serotonin (as with the use of selective serotonin reuptake inhibitors [SSRIs] and other drugs)

H. Norepinephrine (as with the use of serotonin-norepinephrine reuptake inhibitors [SNRIs])

Explanation / Answer

Antipsychotic drugs reduce dopamine levels. In addition to adverse effects occurring with D2 blockade, obnoxious side effects also result from antipsychotics blocking other receptors.

1. For example, blockade of muscaranic cholinergic can result in blurred vision, dry mouth, constipation etc.

2. Antagonists of the histamines receptors result in sedation and weight gain.

3. Blockade at the -receptors for norephinephrine can have an effect on vasodilation and a consequent drop in blood pressure, or orthostatic hypotension.

4. Antagonists of either 1 receptors or 5-HT2 receptors may result in ejaculating dysfunction.

5. Atypical antipsychotics are also known as serotonin-dopamine antagonists (SDAs) because they have higher ratio of serotonin (5-HT2a) to dopamine D2 –receptor blockade than conventional dopamine receptor antagonists. In addition to being potent serotonin type 2A, some SDAs have important anti-cholinergic and anti-histaminic activity.