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53. In Bacteria: Where does RNA polymerase bind to the DNA strand? a. operon b.

ID: 74331 • Letter: 5

Question

53. In Bacteria: Where does RNA polymerase bind to the DNA strand?

                  a. operon

                  b. regulatory gene

                  c. operator

                  d. promotor

                  e. repressor

54. An oncogene is__________________.

                  a. a gene that suppresses tumor growth

                  b. a gene that regulates translation

                  c. a gene that causes cancer

                  d. a gene that enhances photosynthesis and cellular respiration

                  e. a gene that cause RNA synthesis

55. Cigarette smoke is linked to __________ cancer. MARK ALL THAT APPLY.

                  a. bladder

                  b. cervical

                  c. Lung

                  d. kidney

                  e. stomach

56. How can a normal gene become a cancer gene?

                  a. mutation within gene creates hyper-active growth protein

                  b. multiple copies of a gene causes excessive amounts of growth stimulating protein

c. gene moved to new DNA position, under new controlà normal growth stimulating protein produced in excess

d. all of the above

57. Nuclear transplants can be used to clone animals. The first animal animals cloned by this method were__________.

                  a. monkeys

                  b. pigs

                  c. lizards

                  d. frogs

                  e. sheep

58. Complementary DNA (cDNA) can be used to________________.

                  a. replicate DNA sequences

                  b. check for gene expression in a DNA microarray

                  c. transcription and translation of ribozymes

                  d. bind to promotor and regulatory sequences in prokaryotes

                  e. replicate ribosome in the nucleolus

59. _______________________ is an agent that can cause mutations that result in cancer.

                  a. oncogenic substance

                  b. carcinogen

                  c. Tumor promotor

                  d. sarcoma

                  e. melanoma

60. How can multiple proteins/polypeptides produced from a single gene?

                  a. microRNAs

                  b. DNA array

                  c. alternative RNA splicing

                  d. transcription ligase

                  e. exon shuffling

61. Which type of genes regulate development?

                  a. ribosomal

                  b. histones genes

                  c. introns and exons

                  d. regulatory genes

                  e. homeotic genes

62. The black and orange coloring in a tortoise shell cat is the result of __________.

                  a. X inactivation in a cat the is homozygous for coloring

                  b. Y inactivation in a cat the is homozygous for coloring

                  c. X inactivation in a cat the is heterozygous for coloring

                  d. Y inactivation in a cat the is heterozygous for coloring

63. Which cell type would have a gene for insulin?

                  a. muscle cell

                  b. pancreas cell

                  c. liver cell

                  d. white blood cell

                  e. all of the above

64. In Prokaryotes (bacteria): Genes with related functions that’s get transcribed together are called_________.

                  a. an enzyme cluster

                  b. a transcription group

                  c. a translation group

                  d. an operon

                  e. messenger RNA

65. Cancer is ____________. MARK ALL THAT APPLY.

a. most often caused by inherited cancer genes/mutations

b. a result of multiple genetic changes

c. the conversion of proto-oncogenes into oncogenes

d. caused by inactivation of tumor suppresser genes

66. What is Krabbe disease? It is a fatal, inherited_____________

                  a. a cardiovascular disease

                  b. respiratory disease

                  c. nervous system disease

                  d. skeletal system disease

                  e. muscular system disease

67. Gene expression: What is an example of gene regulation/control points that occurs in the nucleus? MARK THREE THAT APPLY.

a. DNA packing/unpacking

b. mRNA breakdown

c. regulation of transcription-example transcription factors

d. breakdown of protein

e. mRNA processing-adding cap and tail

68. What is the approximate number of genes found in the human genome?

a. 100,000

b. 75,000

c. 60,000

d. 50,000

e. 21,000

69. What are enzymes called that recognize and cut specific sequences of DNA?

a. DNA polymerase

b. DNA ligase

c. DNA helicases

d. restriction enzymes

e. reverse transcriptase

70. What are enzymes called that paste strands of DNA together?

a. DNA polymerase

b. DNA ligase

c. DNA helicases

d. restriction enzymes

e. reverse transcriptase

71. Which enzyme is uses mRNA as a template to make a single strand of cDNA (complementary DNA)?

a. DNA polymerase

b. DNA ligase

c. DNA helicases

d. restriction enzymes

e. reverse transcriptase

72. What is taxol (from the pacific yew) used to treat?

a. diabetes

b. anemia

c. HIV/AIDS

d. ovarian cancer

e. none of these

73. Recombinant DNA can be inserted in various organisms. The organism will then make the desired product. Which of the following products is made in genetically modified bacteria? Mark all that apply.

a. tissue plasminogen activator

b. human insulin

c. erythropoietin

d. human growth hormone

74. The uses of the products of DNA technology include__________. Mark all that apply

a. Therapeutic hormones such as insulin

b. Testing for inherited diseases

c. Detecting infectious agents such as HIV

d. vaccines to prevent diseases such as the flu

75. Genetically modified organisms ______________. Mark all that apply.

a. include plants with resistance to herbicides and resistance to pests

b. include plants with an improved nutritional profile

c. include animals with improved qualities

d. include animals that produce proteins or therapeutics

e. raise concerns over introducing allergens into food

76. _____________________ is a method of amplifying a specific segment of a DNA molecule. Pick the best answer.

a.              DNA profiling

b.              Gel electrophoresis

c. Short tandem repeats

d.              polymerase chain reaction

e.              single nucleotide polymorphism

ae.           Restriction digest of DNA

77.___________________ separates DNA molecules based on size. Pick the best and most specific answer.

a.              DNA profiling

b.              Gel electrophoresis

c. Short tandem repeats

d.              polymerase chain reaction

e.              single nucleotide polymorphism

ae.           Restriction digest of DNA

78. Uses of DNA profiling include__________. Mark all that apply.

Evidence to show guilt or innocence

Paternity analysis

Identification of human remains

Species identification as evidence for sale of products from endangered species

79. True or False? The number of proteins in the human proteotome far exceeds the number of total genes found in the genome.

80. How much of our genome do we share with a Chimpanzee?

a. 90%

b. 92%

c. 94%

d. 96%

e. none of these

Explanation / Answer

53. Promoter. - It aids binding of RNA polymerase to initiate transcription.

54. Oncogene - It is a gene which causes cancer.

55. It is linked to lung cancer mainly. But all the other organs listed are also affected due to tobacco.

56. All the above stated conditions are involved in conversion of normal gene to a oncogene.

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